1. Ammo
  3. Rifle Ammunition
  5. 22-250 Remington

22-250 Remington Ammunition for Sale

The .22-250 Remington excels at long-range varmint control and precision target work, pairing lightweight bullets—typically 35 to 55 grains—with a magnum rifle case for razor-flat trajectories and minimal recoil. Match-grade jacketed hollow points and polymer-tipped loads deliver explosive expansion on prairie dogs, coyotes and small predators, while full metal jacket rounds offer consistent accuracy for high-volume range sessions. Popular in bolt-action rifles and AR-style platforms, these cartridges feed reliably and ignite cleanly in both factory and handloaded brass. At Sportsman’s Outdoor Superstore, you’ll find .22-250 Rem ammo from leading manufacturers—compare bullet profiles, check in-stock availability and complete your purchase online with competitive pricing, secure checkout and fast shipping.
22-250 REM 50 GR JHP

Federal 22-250 Remington 50 gr JHP American Eagle Varmint and Predator 20/Box

  • $24.99 $23.99 ($1.20 / round )
In Stock
  • Brand: Federal
  • Item Number: AE22250G
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 50 GR ACCU TIP-V 20/BOX

Remington 22-250 Rem 50 gr Accu Tip-V 20/Box

  • $40.99 $25.99 ($1.30 / round )
In Stock
  • Brand: Remington
  • Item Number: PRA2250RB
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 50 GR V-MAX VARMINT EXPRESS

Hornady 22-250 Rem 50 gr V-Max Varmint Express 20/Box

  • $24.99 $23.99 ($1.20 / round )
In Stock
  • Brand: Hornady
  • Item Number: 8336
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 55 GR JSP SUPER-X

Winchester 22-250 Rem 55 gr Jacketed SP Super-X 20/Box

  • $28.98 $23.99 ($1.20 / round )
In Stock
22-250 REM 50 GR JHP VARMINT/PREDATOR

Federal 22-250 Rem 50 gr JHP American Eagle Varmint and Predator 50/Box

  • $61.99 $58.99 ($1.18 / round )
In Stock
  • Brand: Federal
  • Item Number: AE2225050VP
  • Type: Hunting
  • Quantity: 50 Rounds
22-250 REM 50 GR V-MAX SUPERFORMANCE VARMINT

Hornady 22-250 Rem 50 gr V-Max Superformance Varmint 20/Box

  • $25.99 $24.99 ($1.25 / round )
In Stock
  • Brand: Hornady
  • Item Number: 83366
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 35 GR V-MAX SUPERFORMANCE VARMINT

Hornady 22-250 Rem 35 gr V-Max Superformance Varmint 20/Box

  • $35.04 $25.99 ($1.30 / round )
In Stock
  • Brand: Hornady
  • Item Number: 8334
  • Type: Hunting
  • Quantity: 20 Rounds
AMMO, 22250 REM, 40GR, ELITE SERIES VP, POLY TIP

Sig Sauer 22-250 Rem 40 gr Extreme Expansion Tip Elite Series Varmint and Predator 20/Box

  • $38.99 $29.99 ($1.50 / round )
In Stock
  • Brand: Sig Sauer
  • Item Number: E225VP40-20
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 55 GR V-MAX VARMINT EXPRESS

Hornady 22-250 Rem 55 gr V-Max Varmint Express 20/Box

  • $23.99 $23.49 ($1.17 / round )
In Stock
  • Brand: Hornady
  • Item Number: 8337
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 64 GR POWER-POINT SUPER-X

Winchester 22-250 Rem 64 gr Power-Point Super-X 20/Box

  • $29.99 $27.99 ($1.40 / round )
In Stock
22-250 REM 50 GR HORNADY V-MAX

Federal 22-250 Remington 55 Grain Hornady V-Max Varmint and Predator 20/Box

  • $35.99 $23.69 ($1.18 / round )
In Stock
  • Brand: Federal
  • Item Number: V22250VM2
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 55 GR SP POWER-SHOK

Federal 22-250 Rem 55 gr Soft Point Power-Shok 20/Box

  • $22.95 $28.13 ($1.41 / round )
In Stock
  • Brand: Federal
  • Item Number: 22250A
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 55 GR NOSLER BALLISTIC VITAL-SHOK

Federal 22-250 Rem 55 gr Nosler Ballistic Tip V-Shok 20/Box

  • $39.99 ($2.00 / round )
  • Brand: Federal
  • Item Number: P22250F
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 40 GR V-MAX VARMINT EXPRESS

Hornady 22-250 Rem 40 gr V-Max Varmint Express 20/Box

  • $30.95 $17.99 ($0.90 / round )
  • Brand: Hornady
  • Item Number: 8335
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 55 GRAIN PSP EXPRESS RIFLE 20/BOX

Remington 22-250 Rem 55 Grain PSP Express Rifle 20/Box

  • $22.95 $28.72 ($1.44 / round )
In Stock
  • Brand: Remington
  • Item Number: R22501
  • Type: Target
  • Quantity: 20 Rounds
22-250 REM 50 GR JHP 20/BOX

Remington 22-250 Rem 50 gr JHP UMC 20/Box

  • $22.95 $24.62 ($1.23 / round )
In Stock
  • Brand: Remington
  • Item Number: L22504
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 55 GR BALLISTIC SILVERTIP

Winchester 22-250 Rem 55 gr Ballistic Silvertip 20/Box

  • $36.99 ($1.85 / round )
  • Brand: Winchester
  • Item Number: SCST22250B
  • Type: Hunting
  • Quantity: 20 Rounds
22-250 REM 45 GR JHP

Winchester 22-250 Rem 45 gr JHP 40/Box

  • $45.59 $46.50 ($1.16 / round )
In Stock
  • Brand: Winchester
  • Item Number: USA222502
  • Type: Hunting
  • Quantity: 40 Rounds
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