22-250 Remington Ammunition for Sale

The .22-250 Remington excels at long-range varmint control and precision target work, pairing lightweight bullets—typically 35 to 55 grains—with a magnum rifle case for razor-flat trajectories and minimal recoil. Match-grade jacketed hollow points and polymer-tipped loads deliver explosive expansion on prairie dogs, coyotes and small predators, while full metal jacket rounds offer consistent accuracy for high-volume range sessions. Popular in bolt-action rifles and AR-style platforms, these cartridges feed reliably and ignite cleanly in both factory and handloaded brass. At Sportsman’s Outdoor Superstore, you’ll find .22-250 Rem ammo from leading manufacturers—compare bullet profiles, check in-stock availability and complete your purchase online with competitive pricing, secure checkout and fast shipping.

Hornady 22-250 Rem 55 gr V-Max Varmint Express 20/Box

  • $26.99 $22.99 ($1.15 / round )
In Stock
  • Brand: Hornady
  • Item Number: 8337
  • Type: Hunting
  • Quantity: 20 Rounds

Hornady 22-250 Rem 50 gr V-Max Varmint Express 20/Box

  • $26.99 $24.99 ($1.25 / round )
In Stock
  • Brand: Hornady
  • Item Number: 8336
  • Type: Hunting
  • Quantity: 20 Rounds

Hornady 22-250 Rem 50 gr V-Max Superformance Varmint 20/Box

  • $29.58 $27.99 ($1.40 / round )
In Stock
  • Brand: Hornady
  • Item Number: 83366
  • Type: Hunting
  • Quantity: 20 Rounds

Federal 22-250 Remington 50 gr JHP American Eagle Varmint and Predator 20/Box

  • $41.99 $27.76 ($1.39 / round )
In Stock
  • Brand: Federal
  • Item Number: AE22250G
  • Type: Hunting
  • Quantity: 20 Rounds

Winchester 22-250 Rem 64 gr Power-Point Super-X 20/Box

  • $26.24 ($1.31 / round )
In Stock

Hornady 22-250 Rem 35 gr V-Max Superformance Varmint 20/Box

  • $35.04 $30.92 ($1.55 / round )
In Stock
  • Brand: Hornady
  • Item Number: 8334
  • Type: Hunting
  • Quantity: 20 Rounds

Sellier And Bellot 22-250 Remington 55 gr SP 20/Box

  • $17.80 ($0.89 / round )
In Stock

Winchester 22-250 Rem 45 gr JHP 40/Box

  • $45.59 $53.95 ($1.35 / round )
In Stock
  • Brand: Winchester
  • Item Number: USA222502
  • Type: Hunting
  • Quantity: 40 Rounds

Remington 22-250 Rem 55 Grain PSP Express Rifle 20/Box

  • $38.99 $28.97 ($1.45 / round )
In Stock
  • Brand: Remington
  • Item Number: R22501
  • Type: Target
  • Quantity: 20 Rounds

Hsm 22-250 Remington 55 Grain Sierra Blitz King 20/Box

  • $45.59 $29.26 ($1.46 / round )
In Stock
  • Brand: Hsm
  • Item Number: 2225020N
  • Type: Hunting
  • Quantity: 20 Rounds

Remington 22-250 Rem 50 gr JHP UMC 20/Box

  • $45.59 $26.86 ($1.34 / round )
In Stock
  • Brand: Remington
  • Item Number: L22504
  • Type: Hunting
  • Quantity: 20 Rounds

Federal 22-250 Rem 55 gr Soft Point Power-Shok 20/Box

  • $38.99 $25.68 ($1.28 / round )
In Stock
  • Brand: Federal
  • Item Number: 22250A
  • Type: Hunting
  • Quantity: 20 Rounds

Hsm 22-250 Remington 50 Grain Soft Point Varmint 20/Box

  • $22.95 $24.20 ($1.21 / round )
In Stock
  • Brand: Hsm
  • Item Number: 222504N
  • Type: Hunting
  • Quantity: 20 Rounds

Federal 22-250 Rem 50 gr JHP American Eagle Varmint and Predator 50/Box

  • $22.95 $58.68 ($1.17 / round )
In Stock
  • Brand: Federal
  • Item Number: AE2225050VP
  • Type: Hunting
  • Quantity: 50 Rounds

Nosler 22-250 Rem 55 gr FB Tipped 20/Box

  • $22.95 $37.22 ($1.86 / round )
In Stock
  • Brand: Nosler
  • Item Number: 65155
  • Type: Hunting
  • Quantity: 20 Rounds

Federal 22-250 Remington 55 Grain Hornady V-Max Varmint and Predator 20/Box

  • $43.99 $25.06 ($1.25 / round )
In Stock
  • Brand: Federal
  • Item Number: V22250VM2
  • Type: Hunting
  • Quantity: 20 Rounds

Winchester 22-250 Rem 55 gr Extreme Point Varmint X 20/Box

  • $35.99 $28.12 ($1.41 / round )
In Stock
  • Brand: Winchester
  • Item Number: X22250PXP
  • Type: Hunting
  • Quantity: 20 Rounds

Remington 22-250 Rem 50 gr Accu Tip-V 20/Box

  • $41.99 $23.99 ($1.20 / round )
In Stock
  • Brand: Remington
  • Item Number: PRA2250RB
  • Type: Hunting
  • Quantity: 20 Rounds
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